The benzodiazepine class of drugs, known as tranquilizers, have long been used as drugs or as an adjunct to stimulants. One of these drugs is Phenazepam, a powerful tranquilizer that can cause severe addiction if used incorrectly.
Phenazepam: history and properties
Phenazepam was synthesized in the USSR in 1970 and became the first tranquilizer created in the Soviet Union. Many scientists worked on the synthesis of the tranquilizer molecule, the drug was tested many times and only in the late 70s began to be used in medicine.
Until now, Phenazepam is widely used in medical practice for the following diseases:
- anxiety disorders;
- nervousness;
- phobias, obsessive states;
- psychoses;
- chemical addiction.
The drug is also effective for convulsions and has a hypnotic effect. Phenazepam is also used to prepare the patient for surgery.
The tranquilizer is a white or creamy crystalline powder, odorless and with a bitter taste. The powder does not dissolve in water and is extremely difficult to dissolve in alcohol. This is the first danger of using Phenazepam without a doctor's testimony. It is almost impossible to completely dissolve the medication in alcohol at home, especially when it is done by a person with drug addiction. Small particles of the drug clog blood vessels, form blood clots, which leads to the development of abscesses and gangrene.
Of course, the danger of using Phenazepam does not end there. What makes people risk their lives by using a tranquilizer as a drug?
Narcotic effect of Phenazepam
The effect of taking a large dose of a tranquilizer, including Phenazepam, is reminiscent of drug intoxication with barbiturates. However, there are some features that depend on the type of drug taken. In case of an overdose of Phenazepam, disinhibition and motor activity are observed, which cannot be controlled. A person literally feels the need to move, he feels a surge of strength and elation. Euphoria caused by Phenazepam is also characterized by:
- restlessness;
- sudden switching of attention, inability to concentrate on one thing;
- reduced clarity of perception of images and sounds;
- decreased reaction speed;
- the feeling of flying.
To obtain this effect, you need to take about 4-5 tablets of Phenazepam. But most addicts rarely use the drug as an independent drug. Most often, a tranquilizer is mixed with alcohol or narcotic substances, which makes it possible to intensify the “high” and make it last longer.
When Phenazepam tablets are taken orally, their peak effect begins in about an hour and lasts about 10 hours. Of course, over time, the pleasure from the usual dose disappears and drug addicts begin to inject the drug intravenously, which significantly increases the euphoria, but at the same time causes irreparable harm to health.
Phenazepam, like other tranquilizers, accumulates in the tissues of the body and is released gradually; the effect of a large dose of the drug in combination with other stimulants can last about 2 days. Staying in a state of altered consciousness for so long, a person risks losing his mind.
External signs of drug intoxication
The effect of Phenazepam resembles a state of alcohol intoxication. You can find out that a person has taken a large dose of a tranquilizer by the following signs:
- lack of coordination, unsteady gait;
- talkativeness, an inexplicable desire to communicate (especially noticeable if a person does not like to communicate in a sober state);
- slurred, confused speech;
- pale, bluish skin;
- dilated pupils, poorly responsive to changes in lighting;
- whitish coating on the tongue and entire oral cavity;
- dry eyes and other mucous membranes;
- loss of appetite.
A person can remain in this state for about a day. After the drug wears off, the person feels drowsiness, apathy, and weakness of the limbs (“wobbly” legs).
Just 3-4 weeks of regular use of Phenazepam as a drug is enough to form an addiction to the drug. In the future, the previous dose will no longer cause euphoria, and the person will have to take more and more medication to avoid withdrawal symptoms and get a “high.” Gradually, the drug becomes the only meaning of the addict’s life, destroying his body and psyche.
Phenazepam: a slow-acting poison
Regular use of tranquilizers, especially Phenazepam, has an extremely negative effect on the psyche. Quite quickly, the high from the drug disappears, and the person increasingly finds himself in a state of depression or anger. Irritability, sleep attacks and even hallucinations - all this is faced by a Phenozepam addict.
No less serious destruction awaits the addict’s body. Long-term overdose of Phenazepam leads to problems with:
- Cardiovascular system;
- Genitourinary system;
- Hematopoietic system;
- Nervous system.
Chasing a pill of happiness, a person dooms himself to many pathologies, incurable diseases, including the emergence of severe physical addiction. It is impossible to cope with this disease on your own - only an experienced specialist can help an addict start a new life and avoid the tragic consequences of the disease.
If a severe overdose is allowed, this can be dangerous not only for the nervous system, but also for the functioning of the heart and respiratory organs, since large quantities of this drug suppress the activity of the respiratory center and the functioning of the heart.
Phenazepam acts on the body as a sedative, a sleeping pill, and relieves muscle tension. The drug has an inhibitory effect on the central nervous system. Nerve impulses stop transmitting at normal speed. Under the influence of the drug, brain stem receptors are activated, while neurons in the subcortical layers of the brain become less sensitive. The same thing happens with the receptors of the hypothalamus and thalamus. Under the influence of phenazepam, spinal reflexes become less active.
The drug should not be used without supervision and without a doctor's prescription, as it is a potent tranquilizer.
The use of phenazepam affects blood production. There is a lack of red blood cells, an increase in the number of leukocytes, platelets, which manifests itself in the form of fever, increased body temperature, and lethargy.
Kidney function is disrupted and sexual desire changes. The drug also provokes allergic manifestations, which can include urticaria and itching.
Phenazepam has a very bad effect on the central nervous system of the fetus if a pregnant woman takes it.
To relax muscles, neurological patients should take two to three milligrams of the drug once or twice a day.
If treatment begins with the drug in the form of a liquid for injection, then as soon as the patient’s condition improves, he should be transferred to the tablet form of the drug.
If you are treated with phenazepam for a long time, it provokes addiction, akin to a drug. If, during long-term treatment, you suddenly stop taking the drug, it will cause withdrawal syndrome or “withdrawal.”
People who lead a healthy lifestyle, as a rule, do not have to turn to such drugs.
The use of the drug while pregnant is strictly prohibited, especially the first three months, as well as during breastfeeding. In addition, many doctors consider the drug dangerous for children and adolescents. Therefore, it is not advisable to use it in the treatment of persons under eighteen years of age.
A drug is prescribed for the treatment of schizophrenia, especially for the treatment of those patients who give a negative reaction to the use of other drugs. The drug is prescribed for muscle stiffness, hyperkinesis, athetosis and tics of various origins.
The drug is very serious and for some time now it has been prohibited to sell it in pharmacies without a special prescription from a doctor.
One ampoule of phenazepam contains one milliliter of liquid, including one milligram of the active ingredient. In addition, the liquid contains special medical glycerin, Tween-80, sodium pyrosulphide, caustic soda, and specially prepared water. Ampoules are packaged in blisters of five pieces. There are two blisters in one package. The package comes with a special device for opening ampoules. The ampoule contains a completely transparent and colorless liquid.
The drugs should be stored in a dark place at room temperature.
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Side effects of the drug Phenazepam for patients
Phenazepam, the side effects of which will be discussed below, is a tranquilizer. Used for the treatment of reactive type psychoses, syndromes that cannot be treated with other tranquilizers, neurotic and psychopathic conditions, autonomic dysfunctions and sleep disorders. The drug can relieve causeless fear and emotional stress. It is also used during epilepsy, with tics and hyperkinesis, during the development of rigidity of muscle structures, and autonomic lability.
The medicine is used internally. It greatly affects the activity of various brain structures. Some patients, due to the action of the drug, experience headaches, migraines, a depressed state, or, conversely, causeless agitation.
Can symptoms occur in patients who take an excessive dose?
In case of an overdose of Phenazepam, the instructions for use describe the following symptoms:
- If the dose was relatively moderate, then the patient’s side effects increase or the therapeutic effect of Phenazepam increases.
- With a large dose of overdose, cardiac activity is depressed, breathing problems arise, and the person is in a depressed state.
When should this medication not be used?
Contraindications to the use of this medicine are as follows:
- Comatose or shock state.
- Myasthenia.
- An acute attack of angle-closure glaucoma or a predisposition to this disease.
- Severe diseases of the respiratory system and lungs, which can cause respiratory failure.
- Pregnancy and lactation period. It is especially prohibited to use the drug during the first trimester of pregnancy.
- If the patient is not older than 18 years.
- High human sensitivity to benzodiazepines.
- If the patient complains of a decrease in the ability to remember any information.
Some people treated with this medicine have a tendency to make erratic movements. Many patients experienced myasthenia gravis, dysarthria, and asthenia as side effects.
The drug should not be taken while driving a vehicle or performing work that requires concentration and quick reaction. In children, the medicine causes depression of the central nervous system. Use of this medication with caution is recommended under the following circumstances:
- The patient has renal or liver failure.
- Ataxia of cerebral or spinal type.
- Predisposition to abuse of psychotropic drugs.
- Hyperkinesis and various organic diseases of brain structures.
- During hypoproteinemia.
- Depression.
- If the patient is an elderly person.
A side effect while taking the medication may be a deterioration in the normal functioning of the liver. The main symptom in this case is yellowing of the sclera and skin of the patient. Kidney function may be impaired. Some patients complained of decreased libido. This drug may cause allergic reactions. Long-term treatment with Phenazepam leads to addiction.
What negative effects can this drug cause in patients?
Side effects of Phenazepam are as follows:
- Constant craving for sleep.
- Impaired coordination of movements.
- The person becomes lethargic.
- Brain function noticeably slows down.
- The patient's motor activity decreases.
Some patients stated that they were visited by various visions. But most of the people whom doctors treated with Phenazepam experienced sleep disturbances. This medicine may have a negative effect on blood production. In this case, there is a shortage of red blood cells, which leads to an increase in the number of platelets and white blood cells. The patient's body reacts to this with fever. A person experiences a sharp increase in body temperature and becomes lethargic. Treatment of diseases with Phenazepam often negatively affects the functioning of the patient’s gastrointestinal tract. In this case, he begins to salivate profusely, vomiting and heartburn develop.
In many patients, this leads to an aversion to the food offered, causing constipation or diarrhea.
In patients, the pressure in the blood vessels sharply decreases, body weight drops, and the rhythm of the heart muscle may be disrupted. This drug has a negative effect on the development of the central nervous system of the fetus if the expectant mother takes the drug.
The nature of the side effect and its frequency largely depend on the dose taken, the duration of treatment and the individual sensitivity of the person. If undesirable effects occur, you should stop taking this drug. Before you start using Phenazepam, you should consult your doctor.
Phenazepam overdose: consequences, first aid
- General recommendations for cases of dependence on phenazepam
- Video
Phenazepam is one of the most powerful tranquilizers used to treat various disorders of a person’s psycho-emotional state, such as:
Phenazepam is prescribed by a psychotherapist and dispensed from pharmacies strictly according to a doctor’s prescription. However, more and more often, Phenazepam is being used by customers for other purposes, and unscrupulous pharmacists are selling the psychotropic drug without a prescription to increase daily revenue. The consequences of such a negligent attitude towards a heavy drug are increasingly frequent cases of overdose of Phenazepam. How dangerous is an overdose of Phenazepam and what consequences can it lead to?
The effect of phenazepam on the human body
Phenazepam is in most cases prescribed for a long period - the course of treatment can reach several months. However, the danger of the drug is that with constant use it is addictive. A patient taking Phenazepam can no longer imagine his existence without a new dose of tablets - without them, life seems gray and monotonous, boring and uninteresting to him.
Phenazepam is prescribed to treat mental disorders such as depression. But with excessive consumption of the drug or if the dosage is not observed, Phenazepam can aggravate the depressive syndrome. Existing life problems begin to seem insoluble, to the point that a person sees only one way out - suicide.
Phenazepam is prohibited from being prescribed to people with an unbalanced psyche, since psychotropic pills can cause clouding of consciousness in them and cause a complete lack of understanding of reality.
Failure to comply with the dosage has a number of side effects, one of which is the appearance of hallucinations and euphoria. This “feature” of Phenazepam is of particular interest to drug addicts. The reasonable cost of the drug and unscrupulous pharmacists dispensing the drug without a prescription make Phenazepam an easy target for lovers of non-standard emotions, or, simply put, “highs”.
Exceeding the dosage, self-medication and using Phenazepam for other purposes has one result - poisoning and overdose. Perhaps the worst thing is that, according to statistics, Phenazepam poisoning occurs no less often in children than in adults.
Symptoms of poisoning and overdose
The daily dose of Phenazepam is a maximum of 10 mg, depending on the existing psychological disorder. The dosage is prescribed by the attending physician. Daily intake of up to 20 mg of Phenazepam per day is allowed for serious pathologies of the nervous system and only in a hospital! A single dose of the maximum daily dose (10 mg) leads to inevitable poisoning and overdose, often causing death.
An overdose of phenazepam has characteristic symptoms. It can be determined by the following characteristics:
- overly excited state;
- feeling of euphoria;
- drowsiness;
- increased depression;
- apathy and indifference to everything around;
- excessive salivation;
- nausea;
- vomit;
- spontaneous urination;
- diarrhea or constipation;
- Strong headache;
- dizziness;
- fainting;
- difficulty in controlling your movements, up to complete loss of coordination;
- disorientation;
- inhibited physical reaction;
- clouding of mind, inappropriate behavior;
- partial memory loss;
- serious mental disorders;
- convulsions, severe trembling in the muscles;
- a sharp decrease in blood pressure;
- feeling of body aches, general painful condition;
- dyspnea;
- slow heart rate;
- labored breathing;
- state of stupor.
Ultimately, the most terrible consequence of an overdose of Phenazepam is coma and death. This can happen mainly when taking too many tablets, as well as when combining Phenazepam with alcoholic beverages or narcotic substances.
Phenazepam: a deadly danger for children
Phenazepam is a very strong medicine that has a serious effect on human health. We are primarily talking about harm to the body of an adult, since taking Phenazepam is allowed no earlier than from 18 years of age. The harmful effect of the medicine on the child’s body is many times stronger!
A child may be poisoned by Phenazepam completely accidentally, or he may deliberately try to harm his health.
How is it possible for children to be poisoned by Phenazepam:
- One of the important points of the instructions for using Phenazepam is to store the tablets out of the reach of children. Children are naturally curious, and can mistake pills for candy; in this way, Phenazepam will accidentally cause an overdose and poisoning of the child.
- Almost all modern children are owners of various gadgets - phones, smartphones, tablets. You can find any necessary information freely available on the Internet. Finding themselves in a life situation that is difficult for children to understand, children increasingly seek to escape from it by suicide. As a “solution to the problem,” a teenager can opt for Phenazepam, which is increasingly being advertised on the Internet as a remedy for all life’s problems. According to statistics, more than 20% of child suicides occur through taking a lethal dose of Phenazepam.
A child poisoned by Phenazepam will have characteristic symptoms: vomiting, stupor, hallucinations, loss of coordination, and hearing loss may occur. The result of childhood intoxication is coma and death.
Consequences of poisoning and first aid for intoxication
Phenazepam poisoning is one of the first places in medical overdose. At the insistence of the Ministry of Health, Phenazepam is included in the list of potent drugs, with strictly limited availability from pharmacies. But such sanctions for this medicine did not solve the problem of regular overdoses of pills. Phenazepam overdose and mortality from it continues to rise.
The consequences of poisoning with pills are very diverse, but their final result (if medical care is not provided on time) is the same - death. How can you help a person who has been poisoned by Phenazepam?
- First of all, you need to call an ambulance.
- Before the ambulance arrives, the patient must be given plenty of fluids.
- Urgently perform gastric lavage. To do this, add a little salt to warm water and make the patient drink. And also give him an enema.
- If the patient is conscious, you need to induce vomiting by any available method.
- Be sure to give the poisoned person a sorbent (any one that is in the first aid kit will do - activated carbon, Smecta, Enterosgel, Polysorb, Filtrum).
- Do not leave the patient alone, monitor his condition until the ambulance arrives.
Further treatment should take place in a hospital, under the supervision of medical personnel.
Phenazepam can cause a powerful addiction that needs to be eliminated.
Important: It is worth noting that abrupt discontinuation of the medication is unacceptable! This can lead to serious health problems.
To properly recover from addiction, it is necessary to slowly reduce the daily dosage. For example, if the patient’s average daily intake of tablets was 10 tablets, then it should be reduced to 9 tablets per day. After 3 days, reduce the dosage to 8 tablets per day, after another 3 days - to 7 tablets. Follow this method until the use of Phenazepam is no longer a daily necessity. This gentle method of reducing the dosage will help the body gradually adapt to a new existence, without taking pills.
An antidote will help get rid of addiction to Phenazepam. Flumazenil is a powerful antidote; it helps to neutralize the effect of Phenazepam on a person’s psycho-emotional state.
Depression and stress are serious problems that disrupt a person’s normal life. In pursuit of returning the bright colors of life and complete peace of mind, you should not look for a way out in drug abuse. Any antidepressant and tranquilizer has a temporary effect, helping only to temporarily distract from everyday depressing difficulties. Trying to hide from external problems with a handful of Phenazepam tablets, wouldn't that be a deadly mistake?
Phenazepam - side effects
This drug is not new; it was developed about 40 years ago by Soviet scientists. However, this tranquilizer still remains the most effective among similar drugs. There is also another advantage that Phenazepam has - side effects after taking it occur very rarely and, as a rule, are mild, which ensures good tolerability of the medication.
Side effects of Phenazepam
All negative symptoms are divided into several groups, depending on the organs that are affected.
In relation to the peripheral and central nervous system, the following side effects of Phenazepam are observed:
- dizziness;
- ataxia;
- drowsiness;
- decreased ability to remember and concentrate;
- constant fatigue;
- unsteady gait;
- disorientation;
- confusion;
- slow motor and mental reactions.
This group of symptoms occurs at the very beginning of the course of treatment, more often in older patients, and usually disappears on its own after 7-9 days.
Very rare side effects:
- tremor;
- headache;
- impaired coordination of motor activity;
- euphoria or depression;
- uncontrolled muscle movements, including eye muscles;
- depressed mood;
- myasthenia gravis;
- outbursts of aggression and anger;
- dysarthria;
- epileptic seizures in the presence of epilepsy;
- fear;
- asthenia;
- increased psychomotor excitability;
- suicidal tendencies;
- hallucinations;
- anxiety;
- irritability;
- muscle spasms;
- insomnia.
On the part of the hematopoietic system, the following side effects of Phenazepam tablets occur:
Regarding the digestive organs, taking the medicine may be accompanied by the following symptoms:
- vomit;
- heartburn;
- nausea;
- dry mouth;
- diarrhea or constipation;
- jaundice;
- liver dysfunction;
- decreased appetite.
Side effects from the genitourinary system:
- deterioration of kidney function;
- urinary retention or incontinence;
- dysmenorrhea;
- decrease or pathological increase in libido.
Side effects of Phenazepam in case of overdose
If the dose was exceeded slightly, the tranquilizer effect of the drug may be enhanced, as well as the appearance of allergic reactions on the skin - rash, itching, urticaria.
A strong deviation from the normal portion is characterized by a clear depression of respiratory and cardiac activity and consciousness. Long-term use of Phenazepam in high dosages provokes drug dependence, similar to drug addiction. In this case, side effects:
- decreased blood pressure;
- diplopia;
- weight loss;
- tachycardia;
- withdrawal syndrome when reducing the dose or completely stopping the medication;
- nervousness;
- spasms of skeletal and smooth muscles;
- perception disorders (paresthesia, hyperacusis, photophobia, acute psychosis);
- dysphoria;
- increased sweating;
- depression;
- depersonalization.
Contraindications and side effects of Phenazepam
It is prohibited to use the described medication in the following cases:
The use of Phenazepam during pregnancy, especially during the first trimester, and breastfeeding is also undesirable due to the possibility of developing the following symptoms in the child:
- insufficient development (of the fetus);
- depression of brain and sucking activity;
- allergic reactions.
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Modern view on the use of Phenazepam in neurology and psychiatry
Phenazepam is a psychotropic drug, part of the group of tranquilizers and sedatives that act primarily on the central nervous system.
The main active ingredient of the drug iszepine. In its activity, the drug Phenazepam is superior to its analogues, also providing a pronounced hypnotic, anticonvulsant and muscle relaxant effect.
Its use with other psychotropic hypnotic drugs leads to significant depression of the central nervous system, that is, the effect is enhanced.
After the first oral administration of the drug, its maximum concentration in the blood is observed after an hour and a half, the substance is eliminated within 5-17 hours.
Release form and composition
The drug Phenazepam is available for oral use in the form of tablets of 20 pieces. There is also a solution for intravenous and intramuscular administration. In neurology, medicine is most often used in the form of tablets; it is prescribed in inpatient and outpatient settings.
The injection solution is used extremely rarely, for severe mental disorders in the acute period, when the patient cannot take medications in tablet form.
The effect of Phenazepam on the body
The drug has a complex effect on the body:
- sedative - the medicine depresses the central nervous system, inhibits excitation processes;
Taking the medicine has a complex effect on the processes of the central and peripheral nervous system. Thanks to the drug Phenazepam, a person stops reacting to external stimuli, can sleep normally in case of insomnia, anxiety, fear, panic attacks and nervous twitching of the limbs go away.
The drug relieves seizures well, it is a strong tranquilizer, and therefore is prescribed exclusively by a doctor.
Phenazepam has an effect on the central and peripheral nervous system, and if the dosage is incorrect or in case of self-medication, the risk of disruption of brain function increases, and adverse reactions and actions appear.
Areas of use
The medicine is used in neurology and psychiatry to treat pathologies of the brain and nervous system. The drug has also found active use in the complex treatment of patients with acute and chronic mental disorders.
Indications for use of Phenazepam:
- neurotic and psychopathic disorders of various origins, which are accompanied by anxiety, fear, and impaired consciousness;
- increased feelings of fear, severe irritability and emotional lability;
- advanced neuroses of unknown etiology;
- preparation for surgical operations in order to suppress the central nervous system and eliminate seizures that may interfere with treatment;
- relief of delirium and alcohol withdrawal, that is, elimination of symptoms that arise after a sharp cessation of alcohol by people with alcohol dependence;
- obsessive states, hypochondriacal manifestations caused by disruption of the nervous system or taking other psychotropic drugs.
The tranquilizer is used in neurology more often for a calming effect, to relieve seizures in cases of false epilepsy and for sleep disorders.
The drug can only be prescribed by a neurologist or psychiatrist, selecting an individual dosage.
Contraindications for use
The medicine Phenazepam has the following contraindications for use:
- increased sensitivity of the body to the main active substance;
- visual impairment, eye diseases, including glaucoma;
- acute alcohol poisoning with dysfunction of vital organs;
- respiratory failure, acute pulmonary diseases;
- children under 18 years of age, pregnancy and lactation;
- liver and kidney failure;
- a history of drug dependence;
- acute diseases of the lungs and cardiovascular system;
- organic brain disorders.
Interesting video about Phenazepam - a modern view:
Special patient groups
The drug Phenazepam is contraindicated in children under 18 years of age; treatment with the drug is allowed during pregnancy and lactation, but in practice it is used extremely rarely, replacing it with safer medications.
The effect of the drug on the fetus is unknown and has not been studied enough. It is contraindicated to take it in the first trimester; in the second and third there may be indications, but neurologists more often select other means.
Paradoxical reactions may occur to the drug, therefore it is contraindicated in the case of unknown disorders before a diagnosis is made. In cases of severe depression and suicidal tendencies, the medicine is used with caution.
Dosages and method of administration
The psychotropic drug Phenazepam in the form of tablets is prescribed for oral administration; in inpatient conditions, the daily dosage of the drug is up to 4 mg; for the treatment of convulsive conditions in epilepsy, the dose is increased to 9 mg. For outpatient treatment, up to 0.5 mg of the drug is prescribed once a day.
In order to relieve alcohol withdrawal, the patient is prescribed 5 mg of medication per day. For the treatment of sleep disorders - 1 mg half an hour before rest. The maximum daily dose should not exceed 10 mg.
Phenazepam is actively used in the treatment of personality disorders, especially often with depersonalization, then the daily dose ranges from 3 to 20 mg, depending on the severity. Such a high dosage is due to the fact that patients with depersonalization are resistant not only to the main active ingredient of the drug, but also to negative side effects.
Overdose symptoms and adverse reactions
Adverse reactions to the drug appear if contraindications are ignored or if the dosage is not observed.
It is possible that complications may arise spontaneously when the patient’s body reacts unpredictably to treatment. Adverse reactions may be associated with the wrong combination of psychotropic drugs during complex treatment.
Adverse reactions occur in the central and peripheral nervous system, genitourinary organs, heart, kidneys, and lungs.
Overdose and adverse reactions to the drug Phenazepam:
- From the central nervous system - drowsiness, constant fatigue, inability to concentrate, disorientation, the patient walks unsteadily, and dizziness occurs. In severe cases, the mental disorder that needed to be stopped with the drug worsens, the patient becomes irritable, aggressive, and tremors appear. Depressed mood, suicidal attempts, severe fear, hallucinations and many other associated manifestations may occur.
- From the gastrointestinal tract - dental diseases caused by constant dry mouth, dyspepsia, vomiting and nausea, impaired functioning of the kidneys and liver, jaundice, loss of appetite and complete refusal of food.
- From the excretory organs - urinary retention or incontinence, hematuria, dysmenorrhea, renal failure, impaired libido levels.
- Dermatological symptoms - redness of the skin, rash, itching, hives, swelling;
- Local reactions with intramuscular or intravenous administration of Phenazepam in ampoules - swelling of the skin, venous thrombosis.
In case of overdose, the patient experiences drowsiness, confusion, suppressed reflexes, and rapid heartbeat. First aid consists of gastric lavage, the patient is given activated charcoal, and symptomatic therapy is performed. In severe cases, hemodialysis is prescribed.
Interaction with other drugs
Features of the effect of Phenazepam on the body in combination with other substances:
- combined use with Eidovudine can cause a toxic effect of this drug on the body;
- in Parkinson's disease, the effectiveness of the main drugs for treatment decreases;
- the toxic effect on the body increases when treated with microsomal oxidation inhibitors;
- pharmacological effectiveness increases with the simultaneous administration of neuroleptics, hypnotics and antipsychotic drugs;
- simultaneous use with Clozapine may cause disturbances in the respiratory system.
Thinking out loud
Reviews from practicing doctors and ordinary people who have taken or are taking Phenazepam.
Phenazepam is effective as a sleeping pill. If you take it in moderation and in the indicated dosage, no consequences are observed.
I have been taking the drug daily for three years, I don’t know how safe it is and what the consequences may be. I am afraid of crowded places and sudden death, the medicine dulls the anxiety, but it seems that an addiction has already appeared.
The psychotropic medicine Phenazepam is prescribed for severe neurological and mental disorders. Self-medication or prescribing it to eliminate superficial symptoms is dangerous and not justified.
It can be prescribed only after a thorough diagnosis and for a limited period. There are many contraindications, so you need to work with this drug carefully.
Pros and cons of the drug
Phenazepam is a potent drug, and after taking it a person may behave unpredictably. Among the undeniable advantages of the drug is its effectiveness in the treatment of neuroses, sleep disorders, and epilepsy.
The disadvantage of the drug is its pronounced inhibitory effect on the central nervous system; long-term use of the drug can cause dependence and irreversible changes.
This drug is prescribed quite often in the treatment of neurological and mental diseases, but it still causes controversy among doctors. Many doctors are of the opinion that it is time to replace Phenazepam with modern analogues with a smaller list of adverse reactions.
This section was created to take care of those who need a qualified specialist, without disturbing the usual rhythm of their own lives.
My old mother was ill for three years, sometimes she did not sleep, caring for her, for 3-4 nights. Yes, and when she slept, her brain was always on edge, eavesdropping all night on what was going on in my mother’s room... + my husband has been sick for three years... Sleep was completely disturbed. I started treatment with herbs, valerian, then switched to sleeping pills. Nothing helps. I fall asleep for a couple of hours, sleep for an hour or two, wake up. I fall asleep again for two hours, sleep for an hour and that’s it. I can’t get my sleep in. I do everything I can to get some sleep. I’m living a dream, to fall asleep at 9 pm and wake up at 6 am without waking up... I became nervous, gained a lot of weight, weakness... I’m starting to take phenazepam, then I’ll write back...
Navigation
The drug "Phenazepam" belongs to a large group of tranquilizers of a number of benzodiazepines. It is used to relieve anxiety in patients with neurological and mental diseases. The product helps relieve tension, pathological agitation, and eliminate sleep problems. Due to the nature of its action, the product is not only very effective, but also quite dangerous. Doctors try to prescribe Phenazepam as rarely as possible due to its side effects, a host of contraindications, and the likelihood of developing drug dependence. An overdose of the drug or its combination with alcohol can be fatal.
Contraindications
Phenazepam is a prescription drug that should not be taken without a doctor's permission. Before starting therapy, you must ensure that the patient has no contraindications. Ignoring prohibitions threatens with serious negative consequences, including disruption of the functioning of internal organs, disability, and death.
You will have to abstain from Phenazepam in the following conditions:
- coma - the medication will worsen the depression of the central nervous system. This will complicate the diagnosis of the victim and reduce the effectiveness of treatment measures;
- shock state - when there is a drop in blood pressure to critical levels. “Phenazepam” can increase the severity of the phenomenon and lead to clinical death;
- childhood - the effect of the drug on the body of patients under 18 years of age has not been studied. Theoretically, such actions threaten inhibition of brain function, overdose, and serious side effects due to instability of the central nervous system;
- muscle weakness - under the influence of a tranquilizer it will intensify, which can lead to a malfunction of the internal organs;
- poisoning with medications, drugs or alcohol - increased central nervous system depression threatens respiratory arrest;
- respiratory diseases - pathologies that are accompanied by respiratory failure, with the participation of the Phenazepam composition, can lead to asphyxia;
- deep depression, suicidal tendencies - the medication increases the severity of these manifestations.
The drug used in the third trimester threatens to inhibit the functioning of vital parts of the central nervous system. A baby born against this background will have problems with breathing, reflexes, and feeding. During lactation, the drug is also prohibited due to the high probability of the active ingredient entering breast milk.
Possible side effects of Phenazepam
Taking a tranquilizer can cause an allergic reaction in people with hypersensitivity. If you are intolerant to one of the forms of the product, it is better to refrain from trying to use the second. The immune response to Phenazepam can manifest itself in the form of nausea, vomiting, skin rash, swelling, drop in blood pressure, and anaphylactic shock.
Side effects of the drug against the background of certain diseases:
- stroke - with depressed consciousness, the medication can aggravate the picture;
- hepatitis - if organ damage is accompanied by renal failure, the active substances of the drug will begin to accumulate in the blood and tissues. This threatens the development of an overdose even if therapeutic doses are observed;
- diabetes mellitus - lactose, which is part of Phenazepam tablets, can cause a slight increase in blood sugar levels;
- bradycardia – a tranquilizer makes the pulse even slower, which can lead to disturbances in the functioning of the heart and blood vessels;
- tachycardia - if the phenomenon is caused by excessive blood loss or dehydration, taking the medicine threatens a drop in blood pressure, fainting, and death.
In cases where a medicine poses a danger to the body, the doctor tries to find an adequate replacement for it. Sometimes treatment is still carried out, but requires dose adjustments and monitoring by medical personnel.
Side effects of Phenazepam
The use of a drug that depresses the central nervous system is often accompanied by the appearance of discomfort and alarming signs in the patient.
However, side effects are not always limited to neurological symptoms. They can affect different organs and systems and be weak or strong.
The most common side effects of Phenazepam:
- neurological - muscle weakness, lethargy, decreased reaction speed, daytime sleepiness, decreased concentration. Some patients experience severe headaches and dizziness. There are known cases of problems with memory, speech, and mood swings. Very rarely, taking a tranquilizer leads to an increase in the symptoms against which its action is directed;
- from the reproductive system – decreased libido in both sexes, erection problems in men;
- cardiovascular – slight decrease in blood pressure. In the case of hypotensive patients, this consequence can be dangerous. The product is not recommended for use in patients with blood pressure levels below 90 mmHg. Art. and dehydration;
- from the excretory organs – urinary retention or incontinence;
- dyspeptic – destruction of liver cells, increased activity of liver enzymes.
In most cases, the occurrence of these problems becomes an indication for discontinuation of therapy. The body's negative reaction to Phenazepam does not go away over time and intensifies with continued treatment. After discontinuing the product, impaired body functions are restored within a few days and rarely require symptomatic intervention.
Is it possible to take Phenazepam in old age?
With age, the intensity of the body's defenses and its filters decreases. This is manifested in an increased effect of Phenazepam and its pronounced inhibitory effect on brain function. The result is consequences in the form of lethargy, weakness, and apathy in older patients. To reduce potential risks, before starting therapy, a thorough examination of the patient is carried out, and the standard therapeutic dose is reduced by 20-30%. In general, doctors try not to prescribe a tranquilizer to people over 65 years of age. One of the side effects of the drug at this age is senile dementia and it is impossible to calculate the probability.
What are the dangers of expired tranquilizer Phenazepam?
The shelf life of the medicine in the form of a solution is 2 years, tablets – 3 years. Direct exposure to sunlight and high temperatures significantly reduces these indicators, increasing the danger of the product. Using an expired medication will, at best, not provide the desired therapeutic effect. Such experiments also threaten drug poisoning and intoxication, side effects, and severe allergies.
Side effects of Phenazepam in case of overdose
Even a slight excess of the therapeutic dose of a tranquilizer can lead to negative consequences. If the use of the product is combined with alcohol consumption, such risks increase many times over. Sometimes one tablet of the drug in combination with strong alcohol is enough to provoke deep sleep and vomiting, leading to asphyxia with vomit.
An overdose of a medication can manifest itself as the following symptoms:
- lethargy, drowsiness, slow reactions;
- muscle weakness;
- confusion;
- problems with speech, coordination;
- slow heart rate;
- tremor of the limbs;
- a decrease or sharp drop in blood pressure;
- inability to take full breaths and exhales due to decreased smooth muscle tone;
- coma with a high probability of subsequent death.
It is difficult to calculate the lethal dosage of the drug. The officially recognized formula is 0.5 mg of the active component per 1 kg of adult weight, 0.25 mg per 1 kg of child weight. This is conditional data, since much depends on the age of the victim, his general condition, the presence of alcohol in the blood, and the dosage form of the composition. There are cases when, after 500 mg of Phenazepam, the patient was saved.
Addiction
With prolonged use of the drug, its active substance and metabolites accumulate in body tissues, causing addiction to the drug. Subsequent abrupt refusal of the product leads to the development of withdrawal syndrome. It manifests itself in the form of insomnia, tremor, irritability, anxiety, and increased psychomotor activity. Usually the phenomenon occurs as a result of 2-4 weeks of taking the drug. When using large doses, dependence can develop within a week. To prevent such effects of Phenazepam, you must use the medicine strictly according to the regimen selected by your doctor. The withdrawal of the medication is carried out for 3-5 days, gradually reducing its daily dose.
Treatment with such powerful tranquilizers as Phenazepam is often accompanied by side effects. For this reason, doctors are trying to use the product less and less, replacing it with safer modern analogues. Consumers are still attracted by the low cost of the drug, so they often insist on it themselves, risking their health. The situation is complicated by the ability to purchase medication through online pharmacies without presenting a prescription. Such experiments often result in serious negative consequences.
Phenazepam is a psychotropic drug under special state control. This is not harmless activated charcoal or cough lozenges, but a tranquilizer that has a pronounced anxiolytic (“anti-anxiety”), hypnotic, sedative (calming), anticonvulsant and central muscle relaxant (reducing the tone of skeletal muscles) effect. The international non-proprietary name of this drug - bromod- is difficult to remember even after repeated reading, but this, in fact, is not required: the main thing is to know that phenazepam belongs to the psychotropic drugs of the benzodiazepine series and has all the features inherent in benzodiazepines, while also having in reserve several exclusive pharmacological “trump cards”.
Phenazepam suppresses the activity of the central nervous system, specifically affecting brain structures such as the thalamus and hypothalamus, as well as the limbic system. In close cooperation with gamma-aminobutyric acid (GABA), phenazepam, which has the ability to potentiate the effect of the latter, enhances pre- and postsynaptic inhibition of the transmission of nerve impulses. Activation of GABA receptors consists of stimulation by phenazepam of the GABA-benzodiazepine-chlorionophore prescription complex of benzodiazepine receptors. As a result, the sensitivity of GABA receptors to this mediator increases, thereby enhancing the inhibitory effect of GABA on the central nervous system. At the psychological level, the patient experiences a decrease in emotional stress, restlessness, anxiety, glimpses of a positive attitude, depression and obsessive fears go away.
Phenazepam is available in two dosage forms: tablets and a solution for intravenous and intramuscular administration, and the solution is used mainly to relieve withdrawal symptoms and if necessary, quickly relieve anxiety and psychomotor agitation. The drug is taken under the strict supervision of a doctor in the dosages prescribed by him. In severe (clinical) depression, the drug is even dangerous, because may provoke the patient to commit suicide. Elderly patients or people with a weakened body as a result of any chronic disease should take phenazepam with extreme caution. The risk of developing certain side effects is determined by the individual reaction to the drug of each individual patient, the dose and duration of the therapeutic course. After discontinuation of the drug, unwanted side effects disappear. Long-term use of phenazepam in significant doses, actual abuse of it, is fraught with the development of drug dependence, which is true for any benzodiazepine. Abrupt withdrawal of the drug is also undesirable, because can provoke the so-called rebound syndrome: in relation to phenazepam, its symptoms will be increased depression, irritability, hyperhidrosis - i.e. all those symptoms that were successfully overcome during the course of medication.
Pharmacology
Anxiolytic drug (tranquilizer) of the benzodiazepine series. It has anxiolytic, sedative-hypnotic, anticonvulsant and central muscle relaxant effects.
Strengthens the inhibitory effect of GABA on the transmission of nerve impulses. Stimulates benzodiazepine receptors located in the allosteric center of postsynaptic GABA receptors of the ascending activating reticular formation of the brain stem and interneurons of the lateral horns of the spinal cord; reduces the excitability of subcortical structures of the brain (limbic system, thalamus, hypothalamus), inhibits polysynaptic spinal reflexes.
The anxiolytic effect is due to the influence on the amygdala complex of the limbic system and manifests itself in a decrease in emotional stress, easing anxiety, fear, and restlessness.
The sedative effect is due to the influence on the reticular formation of the brain stem and nonspecific nuclei of the thalamus and is manifested by a decrease in symptoms of neurotic origin (anxiety, fear).
The productive symptoms of psychotic origin (acute delusional, hallucinatory, affective disorders) are practically not affected; a decrease in affective tension and delusional disorders is rarely observed.
The hypnotic effect is associated with inhibition of the cells of the reticular formation of the brain stem. Reduces the impact of emotional, vegetative and motor stimuli that disrupt the mechanism of falling asleep.
The anticonvulsant effect is realized by enhancing presynaptic inhibition, suppresses the propagation of the convulsive impulse, but does not relieve the excited state of the focus. The central muscle relaxant effect is due to inhibition of polysynaptic spinal afferent inhibitory pathways (to a lesser extent, monosynaptic ones). Direct inhibition of motor nerves and muscle function is also possible.
Pharmacokinetics
After oral administration, it is well absorbed from the gastrointestinal tract, T max - 1-2 hours. Metabolized in the liver. T 1/2 - 6-10-18 hours. Excreted mainly by the kidneys in the form of metabolites.Release form
Tablets are white, flat-cylindrical, with a bevel.
Excipients: lactose, potato starch, gelatin, calcium stearate, stearic acid.
10 pieces. - contour cell packaging (5) - cardboard packs.
Dosage
IM or IV (stream or drip): for rapid relief of fear, anxiety, psychomotor agitation, as well as in vegetative paroxysms and psychotic states, initial dose - 0.5-1 mg, average daily dose - 3-5 mg, in severe cases - up to 7-9 mg.
Orally: for sleep disorders - 250-500 mcg 20-30 minutes before bedtime. For the treatment of neurotic, psychopathic, neurosis-like and psychopath-like conditions, the initial dose is 0.5-1 mg 2-3 times a day. After 2-4 days, taking into account effectiveness and tolerability, the dose can be increased to 4-6 mg/day. In cases of severe agitation, fear, and anxiety, treatment begins with a dose of 3 mg/day, quickly increasing the dose until a therapeutic effect is obtained. For the treatment of epilepsy - 2-10 mg/day.
For the treatment of alcohol withdrawal - orally, 2-5 mg / day or intramuscularly, 500 mcg 1-2 times / day, for vegetative paroxysms - intramuscularly, 0.5-1 mg. The average daily dose is 1.5-5 mg, divided into 2-3 doses, usually 0.5-1 mg in the morning and afternoon and up to 2.5 mg at night. In neurological practice, for diseases with muscle hypertonicity, 2-3 mg is prescribed 1-2 times a day. The maximum daily dose is 10 mg.
To avoid the development of drug dependence during a course of treatment, the duration of use of phenazepam is 2 weeks (in some cases, the duration of treatment can be increased to 2 months). When discontinuing phenazepam, the dose is reduced gradually.
Interaction
When used simultaneously, phenazepam reduces the effectiveness of levodopa in patients with parkinsonism.
Phenazepam may increase the toxicity of zidovudine.
There is a mutual enhancement of the effect with the simultaneous use of antipsychotic, antiepileptic or hypnotics, as well as central muscle relaxants, narcotic analgesics, ethanol.
Microsomal oxidation inhibitors increase the risk of toxic effects. Inducers of microsomal liver enzymes reduce effectiveness.
Increases the concentration of imipramine in the blood serum.
When used simultaneously with antihypertensive drugs, the antihypertensive effect may be enhanced. Increased respiratory depression may occur during concomitant administration of clozapine.
Side effects
From the side of the central nervous system and peripheral nervous system: at the beginning of treatment (especially in elderly patients) - drowsiness, feeling of fatigue, dizziness, decreased ability to concentrate, ataxia, disorientation, unsteady gait, slowed mental and motor reactions, confusion; rarely - headache, euphoria, depression, tremor, memory loss, impaired coordination of movements (especially at high doses), depressed mood, dystonic extrapyramidal reactions (uncontrolled movements, including the eye), asthenia, myasthenia gravis, dysarthria, epileptic seizures (in patients with epilepsy); extremely rarely - paradoxical reactions (aggressive outbursts, psychomotor agitation, fear, suicidal tendencies, muscle spasms, hallucinations, agitation, irritability, anxiety, insomnia).
From the hematopoietic organs: leukopenia, neutropenia, agranulocytosis (chills, hyperthermia, sore throat, excessive fatigue or weakness), anemia, thrombocytopenia.
From the digestive system: dry mouth or drooling, heartburn, nausea, vomiting, loss of appetite, constipation or diarrhea; liver dysfunction, increased activity of liver transaminases and alkaline phosphatase, jaundice.
From the genitourinary system: urinary incontinence, urinary retention, renal dysfunction, decreased or increased libido, dysmenorrhea.
Allergic reactions: skin rash, itching.
Local reactions: phlebitis or venous thrombosis (redness, swelling or pain at the injection site).
Other: addiction, drug dependence; decrease in blood pressure; rarely - visual impairment (diplopia), weight loss, tachycardia.
If the dose is sharply reduced or taken is stopped, withdrawal syndrome occurs (irritability, nervousness, sleep disturbances, dysphoria, spasm of smooth muscles of internal organs and skeletal muscles, depersonalization, increased sweating, depression, nausea, vomiting, tremor, perception disorders, incl. hyperacusis, paresthesia, photophobia; tachycardia, convulsions, rarely - acute psychosis).
Indications
Neurotic, neurosis-like, psychopathic and psychopath-like and other conditions (irritability, anxiety, nervous tension, emotional lability), reactive psychoses and senesto-hypochondriacal disorders (including those resistant to the action of other anxiolytic drugs (tranquilizers), obsession, insomnia, withdrawal syndrome (alcoholism, substance abuse), status epilepticus, epileptic seizures (of various etiologies), temporal and myoclonic epilepsy.
In extreme conditions - as a means of facilitating overcoming feelings of fear and emotional stress.
As an antipsychotic - schizophrenia with hypersensitivity to antipsychotic drugs (including febrile form).
In neurological practice - muscle rigidity, athetosis, hyperkinesis, tic, autonomic lability (paroxysms of sympathoadrenal and mixed nature).
In anesthesiology - premedication (as a component of induction anesthesia).
Contraindications
Coma, shock, myasthenia gravis, angle-closure glaucoma (acute attack or predisposition), acute poisoning with alcohol (with weakening of vital functions), narcotic analgesics and hypnotics, severe COPD (possible increased respiratory failure), acute respiratory failure, severe depression (may occur suicidal tendencies); I trimester of pregnancy, lactation period, childhood and adolescence up to 18 years (safety and effectiveness have not been determined), hypersensitivity (including to other benzodiazepines).
Features of application
Use during pregnancy and breastfeeding
During pregnancy, use is possible only for health reasons. It has a toxic effect on the fetus and increases the development of birth defects when used in the first trimester of pregnancy. When taken in therapeutic doses later in pregnancy, it may cause CNS depression in the newborn. Chronic use during pregnancy can lead to physical dependence with the development of withdrawal syndrome in the newborn. Children, especially young children, are very sensitive to the CNS depressant effects of benzodiazepines.
Use immediately before or during childbirth may cause respiratory depression in the newborn, decreased muscle tone, hypotension, hypothermia and weak sucking ("floppy baby" syndrome).
Use for liver dysfunction
Use with caution in case of liver failure.Use for renal impairment
Use with caution in case of renal failure.
Use in children
Contraindicated in children and adolescents under 18 years of age (safety and effectiveness have not been determined).special instructions
Use with caution in case of liver and/or renal failure, cerebral and spinal ataxia, history of drug dependence, tendency to abuse psychoactive drugs, hyperkinesis, organic brain diseases, psychosis (paradoxical reactions are possible), hypoproteinemia, sleep apnea (established or suspected ), in elderly patients.
In case of renal and/or liver failure and long-term treatment, it is necessary to monitor the peripheral blood picture and the activity of liver enzymes.
Patients who have not previously taken psychoactive drugs exhibit a therapeutic response to the use of phenazepam in lower doses compared to patients taking antidepressants, anxiolytics, or alcoholism.
Like other benzodiazepines, it has the ability to cause drug dependence when taken long-term in large doses (more than 4 mg/day). If you suddenly stop taking it, withdrawal symptoms may occur (including depression, irritability, insomnia, increased sweating), especially with long-term use (more than 8-12 weeks). If patients experience unusual reactions such as increased aggressiveness, acute states of agitation, feelings of fear, thoughts of suicide, hallucinations, increased muscle cramps, difficulty falling asleep, shallow sleep, treatment should be discontinued.
During treatment, patients are strictly prohibited from consuming ethanol.
The effectiveness and safety of the drug in patients under 18 years of age have not been established.
In case of overdose, severe drowsiness, prolonged confusion, decreased reflexes, prolonged dysarthria, nystagmus, tremor, bradycardia, shortness of breath or difficulty breathing, decreased blood pressure, and coma are possible. Gastric lavage and activated charcoal are recommended; symptomatic therapy (maintaining breathing and blood pressure), administration of flumazenil (in a hospital setting); hemodialysis is ineffective.
Impact on the ability to drive vehicles and operate machinery
During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Phenazepam is one of the strongest, having the ability to weaken fear and depressive episodes. Causes drowsiness, reduces muscle tone, and its action is directed against.
When exposed to it, the activity of impulses in the nervous system increases, the relief of symptoms of mental and neurological disorders is stimulated, the excitability of subcortical brain processes is reduced, and reflex processes in the spinal cord are inhibited.
It is prescribed to patients with the following diagnoses: increased nervous excitement, irritability, tension, for preventive purposes in states of fear, for the treatment of muscle rigidity and other similar neurological diagnoses.
The drug is also prescribed for some varieties - and to reduce the manifestation of seizures.
Case study and instructions
From a clinical medical point of view, Phenazepam is a safe, fast-acting and sedative. With its help, many tasks are solved, for example, liquefaction of painful sensations in the postoperative period.
Phenazepam is a development of Soviet scientists; the first practical experience of its use was in the seventies of the last century in military medicine.
At that time, this drug was the strongest, sleeping pill. Prescribed to patients with epilepsy, with 
states of anxiety and rehabilitation after prolonged alcohol use.
If the medicine enters the body in its pure form, then the mood can change dramatically in both positive and negative directions. In other words, a surge of strength may be caused or anger may arise.
An overdose affects the normal functioning of internal organs - causing tachycardia, low blood pressure, constipation, diarrhea, vomiting, dry mouth, heartburn.
The hematopoietic system can also malfunction: blood clots form, leukopenia, anemia and other diseases occur. The function of the genitourinary tract is impaired: acute renal failure, urinary incontinence or retention, decreased libido.
– this is a deliberate excess of the dosage in order to change the mental state, which can lead to the development of hepatitis, the appearance of seizures, fever, shortness of breath and will end in death.
Duration and continuity of use leads to addiction, and in cases of abrupt withdrawal from Phenazepam, nervous system disorders, sleep disturbances, hallucinations appear, and sometimes thoughts of suicide occur.
In the UK and EU countries, this drug is used quite rarely for the purpose of treating drug addicts, so that withdrawal symptoms stop for a while or simply to normalize sleep.
This drug has a greater effect on a drug addict than on a person who is simply being treated with this medication. incredible energy and a desire to communicate with people for a long time appear, then it turns into aggression.
To stop taking the drug, it is best to consult a doctor, take the necessary tests and possibly spend some time in the clinic.
Experimental research at the Moscow Research Institute
With the advent of Phenozepam, the treatment of mental illness has become more effective. Research from the Moscow Research Institute has shown that taking the drug for three or five days can relieve symptoms of anxiety, autonomic disorders and sleep disorders.
The problems associated with relieving the symptoms of neurological abnormalities seemed to have been resolved. However, after ten years, cases of abuse and addiction were identified due to exceeding the dose of the drug and taking it for a long time.
Therefore, since the 90s of the last century, a decision was made at the international and domestic level to limit the use of this medicine. However, in the field of minor psychotherapy, Phenazepam remains indispensable. To control the dosage taken, they began to use the form of injections.
The effect of the drug is aimed at the brain, including its cortex and cerebellum. The drug is well absorbed into the blood, and the maximum concentration in the body is reached after 1-2 hours. Discharged after 10 hours.
Studies have shown that anxiety is eliminated already in the first days of use and is fixed for about a month. In affective disorders, the effect of the drug was most significant, and in cases of vital depression it was less effective.
The product also remains indispensable and superior to analogues for sleep disorders, including sudden awakenings and insomnia.
A benzodiazepine tranquilizer is prescribed for epilepsy in combination with other drugs. The practice of doctors and patient reviews have proven that the number of seizures when taking Phenozepam is reduced by half or they disappear completely.
In the treatment of cardiovascular, pulmonary and digestive organs, the drug in small doses has a muscle relaxant, anxiolytic and anticonvulsant effect.
Phenozepam is widely used in cardiological practice for the treatment of tachycardia, cardialgia associated with panic condition and fear of death. With the help of the drug in the complex, the condition is maintained in case of ischemia, headache, arrhythmia. It is used in gynecology to eliminate postmenstrual tension.
All studies and experiments conducted prove that the use of the product is widespread in somatic practice. Before prescribing, it is important to study interactions with other medications. Improper use of other medications after stopping Phenazepam leads to unpleasant consequences, including depression, feelings of fear, muscle twitching, and others.
A word for patients and their relatives
Reviews from people who have taken it and in which they describe their feelings after taking the product will help clarify the situation.
As I got older, it became impossible to just lie down and sleep, I tossed and turned, and in the morning I felt depressed and overwhelmed.
I felt changes in my body. I turned to a specialist and was prescribed Phenazepam. At first I didn’t even want to buy it, knowing that it was addictive to the drug, but I still had to do the first test. Now my sleep has returned to normal, I think it can still be used in small doses.
Valeria
Because of family problems, I started to get nervous, I can’t do anything normally, it’s stressful, and I can’t sleep at all.
A friend convinced me to go to the clinic. They prescribed a drug - Phenazepam. I didn’t believe in its miracle work, but after the first dose I felt that I began to take everything calmly. After 14 days everything returned to normal, and now I don’t take pills at all and feel great. There are, of course, exceptions, but they are rare.
Anastasia
Two years ago I began to suffer from anxiety, and this condition does not allow me to concentrate on the main thing. I turned to a specialist - they prescribed Phenazepam, after the first dose I fell asleep well, and the next morning I began to experience “cottonness” in my head and body. After a few days everything got better.
Nikolay
For two years I was tormented by feelings of fear for my life, for my work, etc. I bought Phenazepam and everything went away on the first day. This is an excellent option for depression, although harmful. What other way out is there?
Maria
The attacks of insomnia lasted about six months, everything caused irritation, so I went to see a doctor. He prescribed this medicine for me. Now I'm fine, thanks to the doctor.
Sergey
The feeling of fear of contraction caused sleep disturbance and a state of depression. I took herbal decoctions, but nothing helped. I had to go to the clinic, where a specialist prescribed me Phenazepam, now I take the drug as prescribed and feel great.
Makar
While actively playing sports, I noticed that my muscles were very tense and could not relax. I consulted with a doctor, he recommended that I take this tranquilizer. After the first days of taking it I didn’t understand anything at all, then I doubled the dose. I began to fall asleep better, and my muscles relaxed.
Eugene
psychomotor agitation in combination with butiferons and aliphatic drugs.
Representatives of drug control are not interested in the drug, since there is no effect on the psyche. For pensioners with sleep disorders, this is one of the best remedies.
Sergey I, general practitioner
A unique benzodiazepine drug in the domestic industry. Copes with sleep disorders, stress and depression. Does not pose a risk of addiction.
It is released strictly according to prescription, and dosages should only be prescribed by a specialist. Cannot be used when working on machine tools, at heights, or when driving vehicles.
Igor Yu, psychiatrist
Summing up
The product has undeniable effectiveness in treating epilepsy, stressful conditions, sleep disorders, and feelings of fear. But with an overdose, all the positive qualities change to the exact opposite, so a sharp change in mood can occur. With long-term use, dependence on the drug develops.
Before using Phenazepam, you should carefully study where side effects and contraindications are indicated, as well as study reviews from doctors and ordinary people.
Practical experience shows that this remedy should be treated with extreme caution and should never be used without a doctor’s prescription. Therefore, experiments are inappropriate here.
